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International Journal of Innovation and Scientific Research
ISSN: 2351-8014
 
 
Saturday 21 July 2018

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QUORUM SENSING EFFECT THE LYSIS MECHANISM OF T4 BACTERIOPHAGE


Volume 10, Issue 2, October 2014, Pages 421–424

 QUORUM SENSING EFFECT THE LYSIS MECHANISM OF T4 BACTERIOPHAGE

Muhammad Kamran Taj, Zohra Samreen, Taj Muhammad Hassani, Imran Taj, and Wei Yunlin

Original language: English

Received 22 August 2014

Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


According to the cell density bacteria can regulate their gene expression. Gene regulation is initiated by the release of signaling molecules into the environment which are called autoinducers. When the population density increases, these autoinducers accumulate extracellularly and these can be detected by the bacteria through quorum sensing.
We found that E. coli make use of indole quorum-sensing signals to prevent it from infection by T4 phage. This has been acknowledged for the first time that E. coli utilizes antiphage defense mechanism regulated by quorum sensing. We proposed that through quorum sensing E. coli is protected in conditions where there is increased risk of infection as for example during growth in high cellular density in which there is mixed species environments. In microbial communities, quorum-sensing is a general phenomenon which controls E. coli susceptibility to phage.


Author Keywords: Quorum, Sensing. Lysis, Mechanism, T4 Bacteriophage.


How to Cite this Article


Muhammad Kamran Taj, Zohra Samreen, Taj Muhammad Hassani, Imran Taj, and Wei Yunlin, “QUORUM SENSING EFFECT THE LYSIS MECHANISM OF T4 BACTERIOPHAGE,” International Journal of Innovation and Scientific Research, vol. 10, no. 2, pp. 421–424, October 2014.