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International Journal of Innovation and Scientific Research
ISSN: 2351-8014
 
 
Thursday 22 August 2019

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Ectopic pregnancy broken after medical treatment by Methotrexate (MTX) : Report of three cases with review of the literature


[ Grossesse extra-utérine rompue après un traitement médical par Méthotrexate (MTX) : A propos de trois observations avec revue de la littérature ]

Volume 19, Issue 2, December 2015, Pages 223–228

 Ectopic pregnancy broken after medical treatment  by Methotrexate (MTX) : Report of three cases with review of the literature

Youssef Benabdejlil, Ghizlane Salek, Ihssane Hakimi, Khalid Guelzim, Jaouad Kouach, Driss Moussaoui, and Mohammed Dehayni

Original language: French

Received 16 May 2015

Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


Medical treatment of ectopic pregnancy (EP) is based on the administration of methotrexate (MTX). It concerns ectopic pregnancy with β-hCG <10000 without cardiac activity and applies to women informed, without history of ectopic pregnancy and who understand the predictive signs of break. These women should always be monitored until β-hCG negativity. The risk of tubal break persists throughout the treatment with MTX. The authors report three cases of ectopic pregnancy treated medically and whose evolution has been marked by a break. They talk through these cases about the indications and limitations of medical treatment and the risks of tubal break under medical treatment.

Author Keywords: Ectopic, pregnancy, Methotrexate, tubal, break.


Abstract: (french)


Le traitement médical de la grossesse extra-utérine (GEU) repose sur l'administration du Méthotrexate (MTX). Il concerne les GEU peu évolutives (β-hCG< 10000 sans activité cardiaque) et s'applique aux femmes informées, compliantes, sans antécédent de GEU et qui comprennent les signes prédictifs de rupture. Celles-ci devront impérativement être surveillées jusqu'à négativation des β-hCG. Le risque de rupture tubaire persistant pendant toute la durée du traitement par MTX. Les auteurs rapportent trois cas de GEU traités médicalement et dont l'évolution a été marquée par une rupture. Ils discutent à travers ces trois observations les indications et les limites du traitement médical ainsi que les risques de rupture tubaire sous traitement médical.

Author Keywords: Grossesse, ectopique, Méthotrexate, rupture, trompe.


How to Cite this Article


Youssef Benabdejlil, Ghizlane Salek, Ihssane Hakimi, Khalid Guelzim, Jaouad Kouach, Driss Moussaoui, and Mohammed Dehayni, “Ectopic pregnancy broken after medical treatment by Methotrexate (MTX) : Report of three cases with review of the literature,” International Journal of Innovation and Scientific Research, vol. 19, no. 2, pp. 223–228, December 2015.