This study focuses on perceived stress and the COVID-19 pandemic among employees of a company in the Gabonese oil sector. It assesses the relationships between the sub-modalities of the covid-19 pandemic (knowledge of the pandemic, compliance with barrier measures and the effect of the pandemic) on perceived stress, on the one hand, and on the other hand the degree of stress perceived among employees diagnosed as co-morbid and not co morbid. The data from a questionnaire submitted to 54 men and women employees made it possible to establish an inter-correlation matrix, linear regressions on the pandemic, perceived stress and the type of employees who participated in this research. At the end of all these analyzes, we record strong and significant links; 1) between the quality of work, professional relationships and perceived stress; 2) between compliance with barrier measures, knowledge of the pandemic, the effect of the pandemic and the perception of COVID-19. To a lesser extent; 3) no difference recorded in the level of perceived stress between co-morbid and non-co-morbid employees while waiting for their results after the screening session.